MLB ALDS odds: Astros and Yankees open as heavy favourites
Justin Verlander is expected to lead the Astros to an ALCS berth. Photo by David J. Phillip/AP.

The MLB wild-card series are coming to an end, and on Tuesday the division series will kick off.

The expanded playoffs field has been whittled down, and we have our division series matchups on the American League side. The two division winners are likely to meet in the ALCS, but MLB's playoffs are well-known for producing upsets.

Here are our MLB ALDS odds.

MLB division series odds

Check out our division series boosts before the best-of-five series get started on Tuesday.

Division series boostsOddsBet now
Three or more games to reach extra innings+105Add to betslip
A no-hitter to be thrown+3,000Add to betslip
Any team to hit a walk-off home run+100Add to betslip
Any team to hit back-to-back home runs-167Add to betslip

Cleveland Guardians vs. New York Yankees MLB ALDS odds

Check out the latest MLB ALDS odds for the Guardians vs. Yankees series. Click linked odds to add selection to your betslip.

Market Odds
Yankees to win the series-205
Guardians to win the series+165
Yankees -1.5 games+140
Guardians +1.5 games-175
Yankees +1.5 games-360
Guardians -1.5 games+280
Yankees to win 3-0+425
Yankees to win 3-1+325
Yankees to win 3-2+325
Guardians to win 3-0+850
Guardians to win 3-1+500
Guardians to win 3-2+500
Games played over/under 3.5Over (-335) or Under (+260)
Games played over/under 4.5Over (+155) or Under (-195)

Odds as of 12:08 p.m. on 10/09/2022.

Why New York is favoured: The Yankees won seven more games than the Guardians in the regular season despite playing in a much tougher division. New York also finished extremely strong going 22-9 in September and October.

How Cleveland could win: The Guardians may have what it takes to counter some of the Yankees' greatest strengths as their lineup is extremely good at putting the ball in play — even against pitchers with big-time velocity. Cleveland's lefty-dominant lineup could also benefit from playing at Yankee Stadium.

Seattle Mariners vs. Houston Astros

Check out the latest MLB ALDS odds for the Mariners vs. Astros series. Click linked odds to add selection to your betslip.

Market Odds
Astros to win the series-240
Mariners to win the series+190
Astros -1.5 games+125
Mariners +1.5 games-155
Astros +1.5 games-480
Mariners -1.5 games+350
Astros to win 3-0+335
Astros to win 3-1+310
Astros to win 3-2+325
Mariners to win 3-0+1,050
Mariners to win 3-1+550
Mariners to win 3-2+550
Games played over/under 3.5Over (-315) or Under (+245)
Games played over/under 4.5Over (+165) or Under (-205)

Odds as of 12:08 p.m. on 10/09/2022.

Why Houston is favoured: The Astros won 16 more games than the Mariners during the regular season, went 12-7 against them in head-to-head matchups and will have home-field advantage. The Astros were 55-26 at Minute Maid Park, making that especially daunting.

How Seattle could win: Luis Castillo showed he could go toe-to-toe with any starter in the wild-card round and the Mariners have plenty of "team of destiny" vibes for bettors who are inclined to go with their gut.

There isn't a strong statistical argument for Seattle, but the randomness of a short series could work in their favour.

NorthStar Bets editorial Insiders have no influence, direct or otherwise, over the setting of odds advertised on our platforms.