NFL Week 12 odds: Eagles look for sharper effort against Packers
The Philadelphia Eagles host the Green Bay Packers on Sunday Night Football. Photo AJ Mast/AP.

NFL fans should be extra thankful (wink, wink) for the expansive slate of football coming in Week 12.

The latest: U.S. Thanksgiving brought with it a delicious triple-header on Thursday, ending a memorable battle between the Minnesota Vikings and New England Patriots. On Sunday, we'll wrap up a full day's slate with the Green Bay Packers and Philadelphia Eagles in a primetime matchup.

Check out the latest NFL Week 12 odds.

NFL Week 12 odds

Visit all our NFL betting markets and get full odds for Week 12.

DateAwayHomeSpreadO/U
Nov. 27RaidersSeahawksSEA -447.5
Nov. 27ChargersCardinalsLAC -2.548.5
Nov. 27RamsChiefsKC -1542
Nov. 27Saints49ersSF -943.5
Nov. 27PackersEaglesPHI -6.546.5
Nov. 28SteelersColtsIND -2.539.5

Odds as of 1:20 p.m. ET on 11/27/2022.

NFL Week 12 odds: Matchup of the week

Kyler Murray is back for a reeling Cardinals team that has its playoff hopes hanging by a thread.

Arizona has lost six of eight games, and Murray shoulders plenty of blame along the way, but he'll ideally be an upgrade over Colt McCoy. Last week, McCoy and the Cardinals only scored 10 points in an ugly effort in Mexico City.

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The Chargers have won three of their past four road games outright, covering all four against the spread. Los Angeles is coming off a solid showing against the Chiefs, and their offence looks like it has new life with receiver Keenan Allen back in the fold.

Futures marketsOddsBet now
Bills to win the Super Bowl+400Add to betslip
Bills to win the AFC championship+190Add to betslip
Eagles to win the NFC championship+225Add to betslip
Patrick Mahomes to win NFL MVP-200Add to betslip
Josh Allen to win NFL MVP+700Add to betslip

Week 12 Sunday Night Football matchup

Green Bay Packers vs. Philadelphia Eagles (-6.5)

In a span of three weeks, the Eagles have gone from inevitable to enigmatic.

A mistake-filled loss to the Commanders in Week 10 was followed by a narrow escape against the Colts in Week 11. Neither of those foes is likely to make the playoffs, and yet Philly looked flat throughout both matchups.

And while the Eagles have only committed nine turnovers (tied for second-fewest in NFL), six of those have come in the past two weeks.

This is an important get-right game for the Eagles, and the stakes are high on the other side, too. Many people have probably written off the Packers already, but they aren't technically dead yet.

But with a loss this week, Green Bay (4-7) fans can stop paying attention to the NFL standings and start watching the NFL's Tankathon page.

NorthStar Bets editorial Insiders have no influence, direct or otherwise, over the setting of odds advertised on our platforms.