Packers vs. Lions Week 12 odds and best bet: Pick Detroit to cover the spread on Thanksgiving
Bet on the Detroit Lions to beat the Green Bay Packers on Thursday. Photo by Ashley Landis/AP.

The Detroit Lions host the Green Bay Packers for their annual Thanksgiving Day game.

The pregame narrative: Green Bay long-dominated the NFC North but now the division belongs to Detroit. The Lions are the class of the group and despite nearly losing to the Chicago Bears on Sunday, are a good pick to win and cover the spread against the Packers.

Below are our Packers vs. Lions odds and best bet for Week 12.

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Packers vs. Lions odds and best bet overview

Click link to add selection to betslip. Note: Lines have changed/market no longer available if grey.

SNF best betOddsBet now ⬇️
Lions -7.5-109Add to betslip

NFL odds as of 12:54 p.m. ET on 11/21/23.

Go to full Packers/Lions betting markets.

Packers vs. Lions odds and best bet

Best Bet: Lions -7.5 (-109)

Rhythm and Bruise, Thunder and Lightning, whatever you want to call it, Detroit has a lethal rushing attack.

Jahmyr Gibbs and David Montgomery are causing nightmares for opposing defences. The duo averaged 5.2 yards per carry against a surprisingly stout Chicago run defence in last week's victory.

NFL Thanksgiving Day boostsOddsBet now ⬇️
Lions, Cowboys & 49ers to all win by 10+ points+615 (was +560)Add to betslip
Any team on Thursday to score 50+ points+440 (was +400)Add to betslip
Goff & Love to each record 250+ passing yards & Over 48.5 points+505 (was +460)Add to betslip
Pollard and Robinson Jr. to both score a TD+485 (was +440)Add to betslip
Aiyuk & Lockett to each record 70+ receiving yards & either to score a TD+740 (was +675)Add to betslip
McCaffrey to record 25+ rushing/receiving yards & score a TD+240 (was +220)Add to betslip

The Bears, who are tied for allowing the fewest rushing yards per carry (3.4), will likely prove to be a much tougher matchup for Detroit than Green Bay.

GB vs. DET betting marketsOdds
Packers moneyline+280
Lions moneyline-375
Packers +7.5-112
Lions -7.5-109
Over 47-110
Under 47-110
Montgomery to score a touchdown-195
Gibbs to score a touchdown-148
Amon-Ra St. Brown to score a touchdown-141
AJ Dillon to score a touchdown+117

The Packers have not done a very good job at limiting opposing rushing attacks. They rank 24 in opponent yards per rush attempt (4.3) this season.

That plays right into the hands of a Lions team running the 10th-most frequently (43.9%) of any team and averaging the fourth-most rushing yards per attempt (4.6) this year.

The early-week injury report also says a lot about both teams as they prepare to get ready on a short week.

Take the better, and healthier, team on a short week of rest.

Key stat: The Lions have won three of their five home games by eight-plus points.

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