NFL Week 1 odds: Dolphins/Jaguars have highest total, Chiefs open season as home favourites

The Dolphins and Jaguars have the highest over/under in the NFL's Week 1 slate. Photo by Doug Murray/AP.

NFL Week 1 has arrived.

The latest: The two-time defending champion Kansas City Chiefs are back in the season-opening slot on Thursday. They host the Baltimore Ravens in a rematch from last year's AFC title game. Elsewhere, the Buffalo Bills welcome the Arizona Cardinals while the New York Jets and San Francisco 49ers close out the slate.

Check out the latest NFL Week 1 odds below.

NFL Week 1 odds

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Baltimore Ravens vs. Kansas City Chiefs

Green Bay Packers vs. Philadelphia Eagles

Arizona Cardinals vs. Buffalo Bills

Carolina Panthers vs. New Orleans Saints

Tennessee Titans vs. Chicago Bears

Houston Texans vs. Indianapolis Colts

New England Patriots vs. Cincinnati Bengals

Jacksonville Jaguars vs. Miami Dolphins

Minnesota Vikings vs. New York Giants

Pittsburgh Steelers vs. Atlanta Falcons

Denver Broncos vs. Seattle Seahawks

Las Vegas Raiders vs. Los Angeles Chargers

Dallas Cowboys vs. Cleveland Browns

Washington Commanders vs. Tampa Bay Buccaneers

Los Angeles Rams vs. Detroit Lions

New York Jets vs. San Francisco 49ers

Betting insights

  • The Chiefs' road to a three-peat begins at home against the Ravens. Kansas City added to its wide receiver core, signing Marquise Brown and drafting Xavier Worthy (though Brown might not be available for Week 1 due to a sternoclavicular joint dislocation). Baltimore made a big splash in free agency, adding Derrick Henry to an already dynamic offence.
  • The NFL goes to Brazil for the first time when the Packers and Eagles collide on Friday of opening week. Philadelphia added running back Saquon Barkley to its lethal offensive attack, while Green Bay aims to build on its strong second half of last season with the addition of Josh Jacobs.
  • Buffalo's season ended familiarly — with a loss to the Chiefs. Entering 2024, the new-look Bills no longer employ Stefon Diggs, Tre’Davious White and Jordan Poyer all departing this offseason. Curtis Samuel and Keon Coleman highlight Josh Allen's newest receiving options.
  • Chicago used the first overall pick in the draft on Caleb Williams and he'll get the start in Week 1 against Tennessee. The Bears also added Rome Odunze in the draft, and Keenan Allen and D'Andre Swift in free agency. Will Levis enters the season as the starting QB for the Titans.
  • The biggest favourites of the week are the Bengals (-8.5), who host the Patriots in Cincinnati. Last season, the Bengals went 6-2 ATS as home favourites.
  • Miami had the No. 2 scoring offence last year, but the over was only 4-5 in its home games last year because expectations were sky high. The Dolphins host the Jaguars in Week 1 and the 49-point over/under is the highest on the schedule.

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